California Services to Science Academy (CSSA) Cohort 2.0

Technical Support and Assistance for Promising and Innovative Prevention Programs

Request for Applications — Opens April 17, 2026

Application must be submitted by 5:00 p.m. PDT on Friday, May 29, 2026.

Applications submitted after the deadline will not be accepted. Please submit your application well in advance of the deadline to avoid last-minute technical difficulties.

The application period closed at 5:00 p.m. PDT on May 29, 2026. Thank you to all applicants.

Funding Opportunity at a Glance

What
To support prevention programs seeking to generate and demonstrate credible evidence of effectiveness for locally developed and innovative substance use disorder (SUD) prevention activities.
Who
Non-profit youth-serving community-based and tribal organizations and counties directly implementing Substance Use Prevention, Treatment, and Recovery Services Block Grant (SUBG)-funded prevention programs authorized to do business in California that provide SUD prevention services to adolescent, youth, and/or adult populations, including families. Priority will be given to organizations serving under-resourced or marginalized communities.
Funding
Up to 8 grantees selected, each receiving up to $102,500
Deadline
May 29, 2026
Project Period
December 1, 2026 – March 1, 2028 (15 months)
Administered By
University of California, Los Angeles, Integrated Substance Use and Addiction Programs (UCLA-ISAP) on behalf of the Department of Health Care Services (DHCS)

Application Timeline

1
RFA Released
April 17, 2026
2
Webinars & Office Hours
April 27, 2026 & May 6, 2026
3
Applications Due
May 29, 2026
4
Review Period
June – July 2026
5
Awards Announced
September 2026
6
Grants Issued & Projects Begin
December 1, 2026

Eligibility Criteria

To be eligible, an applicant must meet all of the following criteria:

  • Non-profit youth-serving community-based or tribal organizations, or counties directly implementing SUBG-funded prevention programs, authorized to do business in California.
  • Provides SUD prevention services to adolescent, youth, and/or adult populations, including families.
  • Has an established prevention intervention that has been implemented for a minimum of two years with identified community and/or under-resourced and/or marginalized communities.
  • Organization is physically located in and delivers SUD prevention services in California.
  • Organization staff have demonstrated experience delivering the novel prevention intervention being evaluated.
  • Organization has a willingness and ability to initiate evaluation project data collection and reporting activities over the course of the project.
  • Organization has the technical capacity to participate in virtual Zoom trainings, Learning Collaboratives, monthly meetings, and ongoing coaching over the course of the project.

Priority will be given to organizations serving under-resourced or marginalized communities.

Proposers' Webinars and Office Hours

UCLA-ISAP staff have scheduled webinars and office hours to review the CSSA Cohort 2.0 funding opportunity and answer questions. Participation in one of the webinars is strongly recommended.

Event
Date & Time
Registration
RFA Review Webinar 1
Monday, April 27, 2026
11:00 a.m. – 12:00 p.m.
Office Hours 1
Thursday, April 30, 2026
3:00 p.m. – 4:00 p.m.
RFA Review Webinar 2
Monday, May 4, 2026
11:00 a.m. – 12:00 p.m.
Office Hours 2
Wednesday, May 6, 2026
10:00 a.m. – 11:00 a.m.

Resources

Download the RFA (PDF) Full Request for Applications document (accessible version)
SUPER Evidence-Based Resource Browse evidence-based prevention practices across California
CSSA Cohort 2.0 Proposed Budget Template (XLSX, accessible version) To apply, download and complete the CSSA Cohort 2.0 Proposed Budget Template, then upload it as part of your application.

Webinar Recordings & Materials

RFA Review Webinar 1 — April 27, 2026

Download Webinar 1 Slides (PDF) Accessible slide deck from RFA Review Webinar 1 (April 27, 2026)

RFA Review Webinar 2 — May 4, 2026

Frequently Asked Questions (FAQ)

General Information

Yes. Organizations may submit more than one application if each application represents a distinct intervention or project.

No. Proposal feedback will not be provided prior to the close of the RFA However, after the award announcements, unsuccessful applicants may request feedback. If you have questions about the application, please email CSSA@mednet.ucla.edu.

There is no single ideal candidate. A variety of program types and organizational scopes are welcome. Existing evaluation systems are not required; however, applicants must meet the eligibility requirements outlined in the RFA and should demonstrate readiness and capacity to fulfill the requirements of the RFA.

Yes. At least one dedicated staff member is expected to consistently attend required project activities.

Combined policy and prevention programs should be conceptualized and reported as a single intervention, with a focus on mechanisms and practice components.

Yes. SUPER may host program information so that other organizations can understand and potentially replicate the intervention.

Yes. The goal of technical assistance is to help participating programs build and generate evidence, including programs that currently use curricula that are not yet evidence-based.

Applicants do not need fully developed evaluation systems. Demonstrated readiness and willingness to build evaluation capacity through CSSA Cohort 2.0 participation are considered sufficient.

No. A monthly progress report template will not be available for applicants to review prior to submitting an application.

Yes. Internally developed curricula are eligible if they meet the two-year implementation requirement and focus on substance use prevention outcomes.

Yes. Interventions must focus on substance use prevention outcomes rather than broader social justice or unrelated goals.

Yes. Organizations may designate a backup staff member to support evaluation activities.

Novel interventions may include programs implemented in new settings or communities, technology-integrated approaches, new interventions, or programs developed to meet specific priority populations.

Yes. If participation in CSSA Cohort 2.0 is successful and the intervention can be clearly defined and documented, it may be added to SUPER.

Eligibility

No. Applicants must currently receive funding through EYC or SUBG in order to be eligible.

If a COE wants to apply as a co-applicant or subcontractor with the county serving as the fiscal lead, the county must be receiving SUBG funding and directly implementing a SUBG-funded prevention program. The lead applicant (county or county behavioral health agency) must indicate within the application that the COE is a co-applicant and/or subcontractor supporting the lead applicant to complete the deliverables of the RFA.

Yes. Organizations currently receiving EYC funding and implementing EYC programs are eligible.

Yes. If a COE receives SUBG funding and directly implements SUBG-funded prevention programs, it is eligible to apply as the lead applicant.

Yes. The intervention proposed for CSSA Cohort 2.0 must be funded through EYC or SUBG.

Yes. Eligibility is limited to current EYC or SUBG funded providers.

Possibly. Eligibility depends on the specifics of the intervention and its alignment with federal regulations and funding requirements. Please email CSSA@mednet.ucla.edu for questions about eligibility requirements.

Yes. Environmental prevention strategies, including coalition-based approaches, are considered eligible examples.

Funding and Budget

Yes. External evaluators may support the work; however, applicants must still identify an internal primary contact person.

Yes. Incentives for youth engagement and participation in data collection activities are allowable. However, incentives for youth engagement and participation for data collection activities must not exceed $30 in value.

Yes. It is recommended and encouraged to involve multiple staff members to participate in the evaluation capacity building process rather than relying on a single evaluator or staff member.

Applicants must complete and upload the required proposed budget template as an attachment and provide a separate narrative justification under Section 4 of the application.

Yes. Funds may support existing programming through evaluation and data collection activities.

Yes. Building internal evaluation capacity, including training and involving multiple staff members, is encouraged.

Yes. The budget includes a line item for consultants if an external evaluator is needed. External evaluators must collaborate with UCLA throughout the project period.

No. The maximum allowable indirect cost rate for this opportunity is 15 percent.

Program Activities and Requirements

No. The intervention must have been implemented for at least two years, but it does not need to have been implemented with the exact same population throughout that period.

Yes. Applicants are encouraged to align evaluation activities with existing programming and operational practices whenever possible.

Yes. The focus should be on substance use prevention outcomes rather than broader mental health and social justice goals.

Yes. Programs with multiple practice components may apply, but combined programs should be reported as a single intervention with clear identification of mechanisms and practice components.

Evaluation activities should focus on youth-reported outcomes related to substance use prevention.

No. Applicants are encouraged to align data collection efforts with existing practices and systems whenever possible.

Last updated: May 28, 2026

Questions?

For questions about the application or CSSA Cohort 2.0 funding opportunity, please contact Carissa Loya at cssa@mednet.ucla.edu with the subject line: CSSA Cohort 2.0 Application Online Help.